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Transient acantholytic dermatosis
Grover's disease (GD), also known as benign papular acantholytic dermatosis,〔 transient acantholytic dermatosis,〔 and persistent acantholytic dermatosis is a polymorphic, pruritic, papulovesicular dermatosis characterized histologically by acantholysis〔Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.〕 with or without dyskeratosis.〔Scheinfeld NS, Mones J. Seasonal variation of transient acantholytic dyskeratosis (Grover’s disease). J Am Acad Dermatol. 2006;55:263-8. PMID 16844509〕 Once confirmed, most cases of Grover's disease last six to twelve months, which is why it was originally called "transient". Unfortunately it may last much longer. Nevertheless, it is not to be confused with relapsing linear acantholytic dermatosis.
==Symptoms==
Grover's disease often starts quite suddenly. There are intensely itchy spots on the central back, mid chest and occasionally elsewhere. Frequently, it follows sweating or some unexpected heat stress.
The itchy eruption lasts an average of 10–12 months. It is characterized by papules and papulovesicles with excoriations occurring on the chest, back, lower sternum, arms, and thighs.〔(Grover's Disease )〕 The papules are most commonly found on the mid chest.
Sometimes the features of Grover's are found in people who do not itch or have a conspicuous rash. Most of the people with Grover's who visit a dermatologist, however, itch a lot.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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